PB-22 POWDER (QUPIC or 1-pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester) is a designer drug offered by online vendors as a cannabimimetic agent, and detected being sold in synthetic cannabis products in Japan in 2013.
PB-22 POWDER (QUPIC or 1-pentyl-1H-indole-3-carboxylic corrosive 8-quinolinyl ester) is an originator drug presented by online sellers as a cannabimimetic specialist, and recognized being sold in engineered cannabis items in Japan in 2013. The construction of PB-22 seems to utilize a comprehension of design action connections inside the indole class of cannabimimetics, in spite of the fact that its plan starting points are muddled.
QUPIC addresses a primarily one of a kind manufactured cannabinoid chemotype, since it contains an ester linker at the indole 3-position, as opposed to the precedented ketone of JWH-018 and its analogs, or the amide of APICA and its analogs. It has an EC50 of 5.1 nM for human CB1 receptors, and 37 nM for human CB2 receptors.
PB-22 produces bradycardia and hypothermia in rodents at portions of 0.33 mg/kg, recommending powerful cannabinoid-like movement. The greatness and length of hypothermia initiated in rodents by PB-22 was outstandingly more noteworthy than JWH-018, AM-2201, UR-144, XLR-11, APICA, or STS-135, with a decrease of internal heat level still perceptible six hours in the wake of dosing. One clinical toxicology concentrate on viewed PB-22 to be the reason for seizures in a human and his canine.
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PB-22 POWDER (QUPIC or 1-pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester) is a designer drug offered by online vendors as a cannabimimetic agent, and detected being sold in synthetic cannabis products in Japan in 2013.
Description
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PB-22 POWDER (QUPIC or 1-pentyl-1H-indole-3-carboxylic corrosive 8-quinolinyl ester) is an originator drug presented by online sellers as a cannabimimetic specialist, and recognized being sold in engineered cannabis items in Japan in 2013. The construction of PB-22 seems to utilize a comprehension of design action connections inside the indole class of cannabimimetics, in spite of the fact that its plan starting points are muddled.
QUPIC addresses a primarily one of a kind manufactured cannabinoid chemotype, since it contains an ester linker at the indole 3-position, as opposed to the precedented ketone of JWH-018 and its analogs, or the amide of APICA and its analogs. It has an EC50 of 5.1 nM for human CB1 receptors, and 37 nM for human CB2 receptors.
PB-22 produces bradycardia and hypothermia in rodents at portions of 0.33 mg/kg, recommending powerful cannabinoid-like movement. The greatness and length of hypothermia initiated in rodents by PB-22 was outstandingly more noteworthy than JWH-018, AM-2201, UR-144, XLR-11, APICA, or STS-135, with a decrease of internal heat level still perceptible six hours in the wake of dosing. One clinical toxicology concentrate on viewed PB-22 to be the reason for seizures in a human and his canine.
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Specialized Information
Formal Name: 1-(5-fluoropentyl)- 8-quinolinyl ester-1H-indole-3-carboxylic corrosive
CAS Number: 1400742-41-7
Atomic Formula: C23H21FN2O2
Recipe Weight: 376.4
Immaculateness: ?almost 100%
Definition: A flawless strong
Grins: O=C(OC1=C(N=CC=C2)C2=CC=C1)C3=CN(CCCCCF)C4=C3C=CC=C4
InChi CodeInChI=1S/C23H21FN2O2/c24-13-4-1-5-15-26-16-19(18-10-2-3-11-20(18)26)23(27)28-21-12-6-8-17-9-7-14-25-22(17)21/h2-3,6-12,14,16H,1,4-5,13,15H2
InChi Key: MBOCMBFDYVSGLJ-UHFFFAOYSA-N
DEA Schedule: I
Lawful status
Starting at 9 May 2014, PB-22 is presently not lawful in New Zealand.
In January 2014, PB-22 was assigned as a Schedule I controlled substance in the United States.
In Ohio, PB-22 is illicit.
Florida additionally has restricted PB-22.
Since 13 December 2014 it is additionally illicit in Germany as a result of adding the substance to the BtMG Anlage II.
As of October 2015 PB-22 is a controlled substance in China
Identification
A legal norm of PB-22 is accessible, and the compound has been posted on the Forendex site of possible medications of misuse.
Delivery and Storage Information
Capacity: – 20°C
Delivery: Room Temperature in mainland US; may differ somewhere else
Strength: ? 3 years
See moreover
5F-PB-22
QUCHIC
APICA
Additional information
100grams, 250grams, 500grams, 1KG, 2KG
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