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5fur-144 CRYSTAL (XLR-11 or 5?- fluoro-UR-144) is a medication that goes about as a powerful agonist for the cannabinoid receptors CB1 and CB2 with EC50 upsides of 98 nM and 83 nM, individually.
It is a 3-(tetramethylcyclopropylmethanoyl)indole subsidiary identified with mixtures, for example, UR-144, A-796,260 and A-834,735, however it isn’t explicitly recorded in the patent or logical writing close by these other comparative mixtures, and seems to have not recently been made by Abbott Laboratories, regardless of falling inside the cases of patent WO 2006/069196. XLR-11 was found to deliver fast, fleeting hypothermic impacts in rodents at portions of 3 mg/kg and 10 mg/kg, recommending that it is of tantamount strength to APICA and STS-135.
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Compound and actual information
Molar mass: 329.459 g·mol?1
A scientific norm for this compound is accessible, and an agent mass range has been posted on Forendex
XLR-11 has been connected to hospitalizations because of its utilization
XLR-11 has been connected to intense kidney injury in certain clients, alongside AM-2201.
XLR-11 was prohibited in New Zealand by being added to the brief class drug plan, compelling from 13 July 2012.
The U.S. Medication Enforcement Administration (DEA) made the manufactured cannabinoids UR-144, XLR11, and AKB48 Schedule I, unlawful medications under the Controlled Substances Act (CSA) for the following two years starting at 16 May 2013.
It has additionally been prohibited in Florida as of December 11, 2012.
Arizona prohibited XLR-11 on 3 April 2013.
XLR-11 is prohibited in the Czech Republic